Acute low back pain and sciatica. Painful muscle spasms associated with the spine (neck and back). Post-operative orthopedic pain. Flare-ups of Osteoarthritis or Rheumatoid Arthritis with muscle stiffness.

Etodolac selectively inhibits the COX-2 enzyme (more than COX-1), which reduces the production of prostaglandins. This stops the sensation of pain and reduces swelling at the site of injury. Thiocolchicoside interacts with GABA and glycine receptors in the central nervous system. It "relaxes" the muscles by blocking the signals that cause them to stay in a painful, contracted state, improving the range of motion.

Common: Dizziness, nausea, stomach upset, or heartburn. Occasional: Diarrhea, skin rash, or mild drowsiness. Serious: Stomach ulcers (with prolonged use), blurred vision, or severe allergic reactions.