Neuropathic Pain: Relieving nerve pain caused by shingles (postherpetic neuralgia) or diabetes (diabetic neuropathy). Epilepsy: Used as an add-on therapy for partial seizures in adults and children. Restless Legs Syndrome (RLS): Helps reduce the urge to move legs, especially at night. Off-label Uses: Sometimes prescribed for hot flashes, anxiety, or insomnia under medical supervision.

Despite its name, Gabapentin does not bind to GABA receptors. Instead:Calcium Channel Binding: It binds to the $\alpha_2\delta$ (alpha-2-delta) subunit of voltage-gated calcium channels in the central nervous system.Neurotransmitter Modulation: By binding here, it reduces the release of excitatory neurotransmitters (like glutamate and substance P), which helps "calm" overactive nerves that cause pain or seizures.

Very Common: Drowsiness (somnolence), dizziness, and fatigue. Common: Blurred vision, weight gain, dry mouth, and swelling of the hands or feet (peripheral edema). Neurological: Unsteadiness (ataxia) or uncontrollable eye movements (nystagmus). Serious: Mood changes, depression, or suicidal thoughts. Note: Do not stop taking it abruptly, as this can trigger seizures or withdrawal symptoms.