Benign Prostatic Hyperplasia (BPH): To treat the symptoms of an enlarged prostate in men. Urinary Retention: To help improve the flow of urine and reduce the feeling of incomplete bladder emptying. Kidney Stones: Sometimes used "off-label" to help small stones pass through the ureter more easily.

Silodosin selectively blocks the alpha-1A receptors located in the prostate and the neck of the bladder. By blocking these receptors, it causes the smooth muscles in these areas to relax. This relaxation widens the urinary passage, allowing urine to flow out of the bladder more freely and with less effort.

Common: Retrograde ejaculation (see FAQs below), dizziness, or a stuffy/runny nose. Cardiovascular: Orthostatic hypotension (a drop in blood pressure when standing up), though this is less common with Silodosin than with older alpha-blockers. Gastrointestinal: Diarrhea or abdominal pain. Vision: "Floppy Iris Syndrome" during cataract surgery.