Treatment of moderate to severe symptoms of BPH; reduces the risk of acute urinary retention (AUR) and the need for surgery.
Treatment of moderate to severe symptoms of BPH; reduces the risk of acute urinary retention (AUR) and the need for surgery.
Tamsulosin relaxes the smooth muscles in the bladder neck and prostate, making it easier to urinate (addresses the dynamic component). Dutasteride inhibits the enzyme responsible for converting testosterone into DHT (dihydrotestosterone), the hormone that causes the prostate to grow. This actually shrinks the prostate over time (addresses the static component).
Impotence, decreased libido, ejaculation disorders (including retrograde ejaculation), dizziness, and orthostatic hypotension (drop in blood pressure when standing up).
It is used to treat Benign Prostatic Hyperplasia (BPH), or enlarged prostate. Tamsulosin relaxes the muscles in the bladder and prostate to improve urine flow, while Dutasteride shrinks the prostate over time by blocking hormonal changes.
Tamsulosin begins working within days to improve urinary flow. However, Dutasteride may take 3 to 6 months to significantly shrink the prostate and show its full clinical benefit.
The modified-release formulation ensures a steady delivery of the medication over 24 hours. This helps maintain consistent relief of symptoms and reduces the risk of sudden blood pressure drops.
No. They must be swallowed whole. Crushing or chewing can interfere with the modified-release mechanism of Tamsulosin and may cause irritation to the mouth or throat from the Dutasteride content.
Yes. Women who are pregnant or may become pregnant should not handle leaking capsules. Dutasteride can be absorbed through the skin and may cause birth defects in a male fetus.
Common side effects include dizziness, lightheadedness (especially when standing up), and sexual side effects such as decreased libido or ejaculation disorders.
Yes. Tamsulosin can cause 'orthostatic hypotension,' a drop in blood pressure when moving from sitting to standing. It is best to take it at the same time each day, usually 30 minutes after a meal.
Yes, Dutasteride typically reduces PSA levels by about 50%. Patients should inform their doctor they are taking this medication so PSA results can be interpreted correctly during prostate cancer screenings.
Yes. You should not donate blood while taking this medication and for at least 6 months after stopping it to prevent the drug from being given to a pregnant woman via transfusion.
It is contraindicated for women, children, and individuals with severe liver disease or a known hypersensitivity to either Tamsulosin or Dutasteride.