Teneligliptin and Metformin Hydrochloride (ER) tablets are used to treat Type 2 diabetes mellitus. This combination helps control high blood sugar levels by increasing insulin production after meals and improving the body's sensitivity to insulin.

'ER' stands for Extended Release. This means the tablet is specially designed to release the medication slowly into your bloodstream over a long period, which helps reduce stomach-related side effects and provides 24-hour glucose control.

No, you should never crush, chew, or break an Extended Release (ER) tablet. It must be swallowed whole with water. Breaking the tablet can cause all the medication to be released at once, increasing the risk of side effects.

Unlike some other diabetes medications, this combination is generally considered weight-neutral. Metformin may even assist with modest weight loss in some patients by improving insulin sensitivity and reducing appetite.

Common side effects include nausea, diarrhea, stomach upset, and headache. Because of the Extended Release (ER) formulation, digestive side effects are usually milder than with immediate-release versions.

It is most effective when taken with a meal, usually dinner. Taking it with food reduces the risk of gastrointestinal issues and helps manage blood sugar levels throughout the night and the following day.

Teneligliptin and Metformin are unlikely to cause hypoglycemia when used alone. However, the risk increases if they are taken in combination with other diabetes drugs like insulin or sulfonylureas.

Lactic acidosis is a rare but serious side effect of Metformin. It is a buildup of lactic acid in the blood and is more common in patients with severe kidney disease, liver problems, or those who consume excessive alcohol.

Teneligliptin is often preferred because it requires less dose adjustment in patients with mild to moderate kidney impairment compared to other drugs in its class. However, the Metformin component requires careful monitoring of kidney function.

It is recommended to avoid excessive alcohol consumption. Alcohol increases the risk of lactic acidosis and can cause unpredictable changes in blood sugar levels, making diabetes management more difficult.